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CARBAMAZEPINE (Tegretol®) can help with seizure (convulsion) control in certain types of epilepsy. Carbamazepine also treats nerve-related pain such as trigeminal neuralgia, or the pain associated with shingles. This medication is not for common aches and pains. Carbamazepine may also be used to control certain mood problems, and is used for manic-depressive illness in some people
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Carbamazepine is used for:
Controlling certain types of seizures and relieving pain in patients with nerve pain in the face, jaw, tongue, or throat.
Carbamazepine is an anticonvulsant. It works by controlling abnormal nerve impulses in the brain. In trigeminal neuralgia, it reduces the activity of nerve impulses in the nerves to the face, decreasing pain.
Do NOT use Carbamazepine if:
you are allergic to any ingredient in Carbamazepine
you are allergic to tricyclic antidepressants (eg, amitriptyline, imipramine, desipramine) or similar medications
you have a history of bone marrow depression, the blood disorder porphyria, or other serious blood disorders
you have a heart condition known as atrioventricular block
you are taking or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using Carbamazepine :
Some medical conditions may interact with Carbamazepine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you are allergic to other seizure medicines (eg, phenytoin, phenobarbital)
if you have a history of increased pressure in the eye (glaucoma), liver or kidney problems, blood problems, heart problems or congestive heart failure, mood or mental problems, seizures, multiple sclerosis, or severe skin reactions (eg, Stevens-Johnson syndrome)
if you consume alcohol-containing beverages or have a history of alcoholism
Some MEDICINES MAY INTERACT with Carbamazepine . Tell your health care provider if you are taking any other medicines, especially any of the following:
Androgens (eg, testosterone), cimetidine, clarithromycin, diltiazem, fluconazole, fluoxetine, fluvoxamine, HIV protease inhibitors (eg, ritonavir), isoniazid, itraconazole, ketoconazole, lamotrigine, loratadine, macrolide antibiotics (eg, erythromycin), nefazodone, niacinamide, progabide, propoxyphene, stiripentol, terfenadine, theophylline, tricyclic antidepressants (eg, amitriptyline), troleandomycin, valproic acid, verapamil, or viloxazine because the side effects of Carbamazepine may be increased
Lithium because the risk of severe nervous system side effects may be increased
Antineoplastics (eg, cisplatin, doxorubicin), felbamate, hydantoins (eg, phenytoin), phenobarbital, primidone, rifampin, or theophylline because the effectiveness of Carbamazepine may be decreased
Acetaminophen, anticoagulants, (eg, warfarin), butyrophenones (eg, haloperidol), clozapine, trazadone, tricyclic antidepressants (eg, amitriptyline), or valproic acid because the side effects of these medicines may be increased by Carbamazepine
Anticoagulants (eg, warfarin), benzodiazepines (eg, alprazolam), birth control pills (eg, ethinyl estradiol/norethindrone) or any other hormone-type contraceptive (eg, levonorgestrel implant), butyrophenones (eg, haloperidol), clozapine, corticosteroids (eg, hydrocortisone), cyclosporine, doxycycline, erlotinib, ethosuximide and its derivatives, etretinate, felbamate, felodipine, HIV protease inhibitors (eg, ritonavir), HMG-CoA reductase inhibitors (eg, simvastatin), imatinib, itraconazole, lamotrigine, methylphenidate, nifedipine, nondepolarizing muscle relaxants (eg, vecuronium), praziquantel, quetiapine, sertraline, tiagabine, topirimate, tricyclic antidepressants (eg, amitriptyline), or voriconazole because the effectiveness of these medicines may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Carbamazepine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Carbamazepine :
Use Carbamazepine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Carbamazepine may be taken with or without food.
Take Carbamazepine regularly to receive the most benefit from it.
Taking Carbamazepine at the same time each day will help you remember to take it.
Eating grapefruit or drinking grapefruit juice may affect the amount of Carbamazepine in your blood. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
If you miss a dose of Carbamazepine , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Carbamazepine .
Important safety information:
Important safety information about Carbamazepine :
Carbamazepine may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Carbamazepine . Using Carbamazepine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
Carbamazepine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Carbamazepine . Use sunscreen or protective clothing if you must be outside for a prolonged period of time.
Before you have any medical or dental surgery, tell your doctor or dentist that you are taking Carbamazepine .
Carbamazepine may interfere with certain lab tests, including thyroid function tests. Be sure your doctor or laboratory personnel know you are taking Carbamazepine .
This medicine may interfere with some pregnancy test results. Check with your doctor or pharmacist if you are taking Carbamazepine and have questions or concerns about the result of a pregnancy test.
LAB TESTS, including blood cell counts, blood iron levels, liver function, kidney function, eye exams, and carbamazepine blood levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
PREGNANCY and BREAST-FEEDING: Carbamazepine has been shown to cause harm to the fetus. Avoid becoming pregnant while taking Carbamazepine . If you think you may be pregnant, discuss with your doctor the benefits and risks of using Carbamazepine during pregnancy. Carbamazepine is excreted in breast milk. Do not breast-feed while taking Carbamazepine .
Possible side effects of Carbamazepine :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Blurred vision
confusion
dizziness
drowsiness
dry mouth or throat
headache
nausea
unsteadiness
vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
bone, joint, or muscle pain
chills
fainting
fast or irregular heartbeat
fever
hair loss
hallucinations
involuntary muscle movements
pain, tenderness, or unusual swelling in the neck, groin, or under the arms
rapid eye movement
reddened, blistered, or swollen skin
ringing in the ears
seizures
severe sweating
shortness of breath
sore throat
stomach pain
swelling of ankles or fingers
ulcers or sores in the mouth
unusual bruising or bleeding
vision changes
yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.
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